Bioactivity of M_2O-TiO_2-SiO_2 (M=Na,K) Glasses : An In vitro Evaluation

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Abstract

The formation of biologically active bonelike apatite on the surfaces of glasses and glass-ceramics is an essential condition for their bonding living bone. In the present study, apatite formation on the surfaces of M<sub>2</sub>O–TiO<sub>2</sub>–SiO<sub>2</sub> (M = Na, K) glasses was examined in a simulated body fluid with ion concentrations nearly equal to those of human blood plasma in order to evaluate their bioactivity. While none of the Na<sub>2</sub>O–TiO<sub>2</sub>–SiO<sub>2</sub> ternary glasses formed the surface apatite, K<sub>2</sub>O–TiO<sub>2</sub>–SiO<sub>2</sub> glasses, not only as SiO<sub>2</sub>-rich glasses but also as TiO<sub>2</sub>-rich glasses, formed the apatite. The alkali ions in the glasses exchanged with H<sub>3</sub>O<sup>+</sup> ions in the fluid. The TiO<sub>2</sub>-rich or SiO<sub>2</sub>-rich hydrogel which was formed on the surfaces of the glasses induced apatite nucleation. The increased degree of the supersaturation of the fluid with respect to the apatite due to the increase in pH provided favorable conditions for apatite nucleation. This indicates that alkali titanates as well as alkali silicates can be basic components of bioactive glasses.

Journal

  • Bulletin of the Chemical Society of Japan

    Bulletin of the Chemical Society of Japan 69(8), 2387-2394, 1996-08-15

    The Chemical Society of Japan

References:  29

Cited by:  3

Codes

  • NII Article ID (NAID)
    10008907816
  • NII NACSIS-CAT ID (NCID)
    AA00580132
  • Text Lang
    ENG
  • Article Type
    Journal Article
  • ISSN
    00092673
  • NDL Article ID
    4060564
  • NDL Source Classification
    ZP1(科学技術--化学・化学工業)
  • NDL Call No.
    Z53-B35
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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