横行結腸癌を合併したターナー症候群の1例  [in Japanese] A CASE OF TURNER'S SYNDROME ASSOCIATED WITH TRANSVERSE COLON CANCER  [in Japanese]

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Abstract

ターナー症候群に消化器系の悪性腫瘍が合併することは極めて稀である.今回,本邦では第1例目と思われる横行結腸癌を合併したターナー症候群の1例を経験したので報告する.症例は40歳,女性.便秘・肝機能障害を主訴に受診.注腸造影検査・腹部CT検査にて多発性肝転移を伴う横行結腸癌と診断され入院.原発性無月経の経歴と低身長・眼瞼下垂・顔面白斑・翼状頸・被髪部低位・楯状胸・乳房未発達・陰毛欠如などの身体所見があり,染色体検査にて45, X/46, X, i (Xq)のモザイク型ターナー症候群と判明した.横行結腸切除(D3)と共に肝外側区域・S5亜区域切除術を施行した.ターナー症候群に合併する非性腺系悪性腫瘍では,唯一結腸癌にのみ相関ありとする報告があり,本邦では自験例が第1例目と考えられる.ターナー症候群においては結腸癌の合併も念頭において診療にあたる必要がある,と考えられた.

Turner's syndrome is rarely associated with malignant neoplasms of the digestive system. We treated a case of Turner's syndrome with transverse colon cancer, thought to be the first case in Japan. A 40-year-old woman with constipation and liver dysfunction was admitted under a diagnosis of transverse colon cancer with liver metastasis, based on barium enema and abdominal computed tomography (CT). She had a history of primary amenorrhea and physical examination showed short statue, ptosis, facial leukoderma, mildly webbed neck, low hairline, shield-like chest, lack of breast development, and no pubic hair. Chromosomal analysis revealed Turner's syndrome with 45, X/46, X, i (Xq) mosaicism, for which we conducted transverse colectomy (D3), hepatic lateral segmentectomy, and subsegmentectomy (S5). Only colonic cancer among nongodanal malignant neoplasms is correlated with Turner's syndrome, and she is thought to be the first case in Japan. The complication of colonic cancershould thus be taken into account in the management of Turner's syndrome.

Journal

  • Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)

    Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 63(6), 1481-1485, 2002-06-25

    Japan Surgical Association

References:  16

Codes

  • NII Article ID (NAID)
    10008914019
  • NII NACSIS-CAT ID (NCID)
    AA11189709
  • Text Lang
    JPN
  • Article Type
    NOT
  • ISSN
    13452843
  • Data Source
    CJP  J-STAGE 
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