11歳小児の舌扁平上皮癌の1例  [in Japanese] Carcinoma of the tongue in an 11-year old child: A case report  [in Japanese]

Access this Article

Search this Article

Author(s)

    • 中島 逸男 NAKAJIMA Itsuo
    • 獨協医科大学耳鼻咽喉科気管食道科 Department of Otorhinolaryngology and Bronchoesophagology, Dokkyo University School of Medicine
    • 吉田 博一 YOSHIDA Hirokazu
    • 獨協医科大学耳鼻咽喉科気管食道科 Department of Otorhinolaryngology and Bronchoesophagology, Dokkyo University School of Medicine
    • 中村 昭彦 NAKAMURA Akihiko
    • 獨協医科大学耳鼻咽喉科気管食道科 Department of Otorhinolaryngology and Bronchoesophagology, Dokkyo University School of Medicine
    • 馬場 廣太郎 BABA Kohtaro
    • 獨協医科大学耳鼻咽喉科気管食道科 Department of Otorhinolaryngology and Bronchoesophagology, Dokkyo University School of Medicine

Abstract

11歳の男児が耳痛を主訴に近医を受診した.局所治療を受けたが症状が軽快しないめ他院を受診した.そこで舌の腫瘤を発見され, 精査・加療目的に当科を紹介された.病変は右舌縁から口腔底にかけ表面不整な潰瘍を呈し, 周囲の硬結は舌正中を越えていた.生検にて高分化の扁平上皮癌と診断された.画像診断も含めた全身検索の結果, 入院時病期分類はT4N0M0 stage IVと診断された.化学療法 (5-Fiuorouracil, Cisplatin) 2クール施行したところ腫瘍はわずかに反応を示し, 縮小するかと思われた.しかし, その後の放射線外照射中にも腫瘍は増大し両側の扁桃窩まで広がりをみせ, 3回の動注化学療法も効果なく, 初診から10ヵ月後に死亡した.

This case was an 11-year old child with a chief complaint of earache whose symptons had not improved despite a treatment at a nearby clinic. He was referred to our department for a treatment of his tongue tumor. The lesion presented an ulcerative picture with an irregular surface traversing the floor of the mouth and accompanied in duration extending beyond the median sulcus of the tongue . A biopsy revealed a highly differentiated squamous cell carcinoma . The disease staging at admission was diagnosed as T4N0M0 stage IV from the results of a general examination, including those of imaging diagnosis. The tumor responded slightly to two courses of chemotherapy (5-Fluolouracil and Cisplatin) and appeared to be reduced. However, it expanded to bilateral tonsil fossa even during external irradiation . The patient died 10 months after his first visit without showing response to intra-arterial chemotherapy administered three times.

Journal

  • Stomato-pharyngology

    Stomato-pharyngology 13(2), 195-201, 2001-02-28

    Japan Society of Stomato-pharyngology

References:  16

Cited by:  1

Codes

Page Top