Cushing's Syndrome with a Large Pituitary Adenoma Producing both Corticotropin-releasing Hormone (CRH) and Adrenocorticotropin (ACTH).
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- YAMADA Yuya
- The Department of Internal Medicine, Sumitomo Hospital
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- OHASHI Akiko
- The Department of Pathology, Sumitomo Hospital
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- INOUE Toru
- The Department of Internal Medicine, Sumitomo Hospital
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- SAKAGUCHI Katsuhiko
- The Department of Internal Medicine, Sumitomo Hospital
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- TSUJIMURA Takahiro
- The Department of Pathology, Sumitomo Hospital
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- OKAMOTO Daisuke
- The Department of Urology, Sumitomo Hospital
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- ITATANI Hiroaki
- The Department of Urology, Sumitomo Hospital
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- FUJIMOTO Naomi
- The Department of Neurosurgery, Tokushima Municipal Hospital
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- KUSAKA Kazumasa
- The Department of Neurosurgery, Tokushima Municipal Hospital
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- FUSHIMI Hisako
- The Department of Internal Medicine, Sumitomo Hospital
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A 57-year-old man showed high serum cortisol, plasma adrenocorticotropin (ACTH) and corticotropin-releasing hormone (CRH) levels with a large pituitary tumor and a prostatic cancer. High dose dexamethasone did not suppress cortisol secretion and CRH administration did not stimulate cortisol secretion. After surgical removal of the pituitary tumor, plasma CRH, ACTH and serum cortisol levels were normalized. Histological examinations showed pituitary adenoma and prostatic adenocarcinoma, and pituitary adenoma was stained with both anti-CRH and anti-ACTH antibodies, but prostatic cancer was not stained. A CRH-producing pituitary adenoma is a new type of Cushing's syndrome.<br>(Internal Medicine 41: 549-554, 2002)
収録刊行物
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- Internal Medicine
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Internal Medicine 41 (7), 549-554, 2002
一般社団法人 日本内科学会
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詳細情報 詳細情報について
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- CRID
- 1390282679844223744
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- NII論文ID
- 10009277998
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- NII書誌ID
- AA10827774
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- COI
- 1:STN:280:DC%2BD38zosVCisw%3D%3D
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- ISSN
- 13497235
- 09182918
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- NDL書誌ID
- 6217111
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- PubMed
- 12132523
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可