A Patient with Acquired Pure Red Cell Aplasia Showing a Positive Antiglobulin Test and the Presence of Inhibitor against Erythroid Precursors.
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- OKOSHI Yasushi
- Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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- IMAGAWA Shigehiko
- Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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- HIGUCHI Masato
- Chugai Pharmaceutical Co., Ltd.
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- YOSHIDA Chikashi
- Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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- SHIMIZU Seiichi
- Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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- MUKAI Harumi Y
- Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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- KOMENO Takuya
- Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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- HASEGAWA Yuichi
- Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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- NINOMIYA Haruhiko
- Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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- KOJIMA Hiroshi
- Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
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- NAGASAWA Toshiro
- Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
書誌事項
- タイトル別名
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- Patient with Acquired Pure Red Cell Aplasia Showing a Positive Antiglobulin Test and the Presence of Inhibitor against Erythroid Precursors
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抄録
A 66-year-old Japanese man developed severe anemia and erythroid hypoplasia in bone marrow without any significant underlying disease. The results of an antiglobulin test were strongly positive, and serum erythropoietin (Epo) was high. The patient was diagnosed as having acquired pure red cell aplasia (PRCA) and was treated with steroids. Anemia was subsided by reticulocyte production in parallel with a decrease in the titer of antiglobulin test and the level of Epo. We studied the immunological mechanism directed against erythroid cells in vitro by using the patient's serum. In vitro analysis indicated the presence of an inhibitor of erythroid precursors at onset, and its disappearance at remission, suggesting the presence of inhibitor against erythroid precursors.<br>(Internal Medicine 41: 589-592, 2002)
収録刊行物
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- Internal Medicine
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Internal Medicine 41 (7), 589-592, 2002
一般社団法人 日本内科学会
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390282679844236416
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- NII論文ID
- 10009278160
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- NII書誌ID
- AA10827774
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- COI
- 1:STN:280:DC%2BD38zosVCiuw%3D%3D
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- ISSN
- 13497235
- 09182918
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- NDL書誌ID
- 6217276
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- PubMed
- 12132531
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可