Oropharyngeal manifestations of primary and secondary syphilis

  • Yoda Keiko
    Department of Otorhinolaryngology, Daihi Hospital, Tokyo Women's Medical University

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Other Title
  • 口腔・咽頭梅毒

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Abstract

Twenty-three cases of primary and secondary syphilis with oropharyngeal lesions were observed in 23 patients referred to the Ear, Nose and Throat Clinic of Daini Hospital, Tokyo Women's Medical University, during an 18-year period (1983-2000). There were 10 females and 13 males, and their ages ranged from 16 to 75 years (mean, 39.2 years). Their chief complains were oropharyngeal pain, pharyngeal paresthesia, eruption of lips or angles of the mouth, glossalgia, and cervical lymphadenopathy, in order of frequency. Two patients showed primary chancres on the lip (11%). Twenty-one presented mucous membrane lesions of secondary syphilis presented: butterfly appearance on bilateral palates and tonsils in 11 (47%), mucous patches on the tongue and/or pharynx in 6 (32%), angular stomatitis in 2 (11%) and erythema on pharyngeal mucosa in 1 (5%). Tertiary syphilis was not experienced. Secondary syphilis with genital lesions were in 7 (30%) and without them in 14 (61%). Four patients of secondary syphilis had extragenital cutaneous lesions, including psoriasiform papular on palm in 2. In 7 patients consulted after 1998, 1 female and 6 males, 3 were HIV-seropositive men who have sex with men, indicating an increasing number of oropharyngeal lesions of syphilis coinfected with HIV in recent years. In ENT clinics, attention should be given to the oropharyngeal lesions of syphilis with or without generalized cutaneous manifestations such as maculopapular eruption or alopecia in a sexually active population.

Journal

  • Stomato-pharyngology

    Stomato-pharyngology 14 (3), 255-265, 2002

    Japan Society of Stomato-pharyngology

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