ホルモン療法により延命効果を認めた腸間膜デスモイド腫瘍の1例

• 寺山 裕嗣

  小林病院外科

• 山本 康弘

  小林病院外科

• 松田 年

  旭川医科大学第2外科

• 菊地 一公

  小林病院外科

• 山口 聖隆

  小林病院外科

• 小林 達男

  小林病院外科

書誌事項

タイトル別名

• A CASE OF MESENTERIC DESMOID TUMOR SUCCESSFULLY TREATED BY ENDOCRINE THERAPY

抄録

A 16-year-old girl was operated on for unknown perforation of the transverse colon on May 14th, 1995. Her family has a kindred of familial adenomatous polyposis (FAP), however, she had no polyps of the colon. After the surgical treatment, we adopted unresectable tumors in the mesenterium of the small intestines. A biopsy of the tumors showed fibromatosis (desmoid tumor). In the knowledge that breast cancer as well as desmoid tumor is dependent on hormone, we instituted the same endocrine therapy against the desmoid tumors; goserelin acetate (3.6mg/month), tamoxifen (20mg/day) and fadrozole hydrochloride (2mg/day). We recorded the tumor's fluid degeneration and a decrease in size over an 8 month period.<br> Desmoid tumors are pathologically benign, but locally invasive and said to be recurrent in a high rate after the surgical treatments. We got sufficient response to treat the desmoid tumor by endocrine therapy without severe side effects. Henceforth, endocrine therapy rather than surgery will be one of the strategies against desmoid tumors.

収録刊行物

• 日本臨床外科学会雑誌

  日本臨床外科学会雑誌 61 (11), 3060-3065, 2000

  日本臨床外科学会

キーワード

• 家族性大腸ポリポーシス(FAP)
• デスモイド腫瘍
• ホルモン療法

詳細情報

• CRID: 1390001204849650560
• NII論文ID: 130003601708
• NII論文ID: 10009382303
• NII書誌ID: AA11189709
• DOI: 10.3919/jjsa.61.3060
• ISSN: 18825133
• ISSN: 13452843
• ISSN: http://id.crossref.org/issn/13452843
• Web Site: http://www.jstage.jst.go.jp/article/ringe1998/61/11/61_11_3060/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2001115636
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可