上顎洞真菌症の１例　　微生物学的検討

DOI 被引用文献1件 参考文献19件

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  • A case of mycosis of the maxillary sinus: A microbiological study.
  • a microbiological study
  • 微生物学的検討

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We studied growth and drug susceptibility of fungi and bacteria isolated from patients with mycosis of the maxillary sinus. In culture specimens from sinusitis dentalis suspected to be caused by mycosis, Aspergillus fumigatus, Streptococcus constellatus, Peptostreptococcus anaerobius, Prevotella intermedia, and Prevotella sp. were isolated. A. fumigatus blocked the growth of the other test organisms. MICs of amphotericin B, nystatin, miconazole, and bifonazole against A. fumigatus were low. However, MICs of griseofulvin, flucytosine, and fluconazole against A. fumigatus were high. Pr. intermedia and Pr. sp. were resistant to β-lactam antibiotics and produced β-lactamases.<BR>Our results suggest that maxillary sinus mycosis was triggered by an attack of sinusitis dentalis due to oral bacteria. Next, A. fumigatus invaded the lesion and held a dominant position in the resulting mycosis. When administering chemotherapy, attention should be paid not only to fungi and bacteria but also to sensitive fungi and bacteria and resistant strains.

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