術後の上顎洞に発生した扁平上皮癌

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  • SQAUMOUS CELL CARCINOMA ARISING FROM THE POSTOPERATIVE MAXILLARY SINUS

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Cancer rarely arises from the maxillary sinus where previously treated with surgery for chronic sinusitis. We report a case of maxillary sinus carcinoma found in a patient with a past history of radical surgery for chronic sinusitis. A brief review of the literature is also presented.<br>The inner surface of the maxillary sinus was principally covered with pseudostratified ciliated columnar epithelium, whereas maxillary sinus carcinoma is histologically classified as sqaumous cell carcinoma in most cases. In the process of carcinogenesis, maxillary epithelium may exhibit serial changes from squamous metaplasia, to atypism, then to carcinoma in situ, and finally to invasive carcinoma. A similar process of carcinogenesis was considered in the present case where cancer arose from nearly normal epithelium regenerated in the postoperative maxillary sinus.<br>Although cancer rarely arises from the maxillary sinus with a history of radical surgery for chronic sinusitis, we reported this case to remind clinicians of the possibility of malignancies to originate from postoperative sinuses. Care should be taken not to overlook carcinoma during surgery for recurrent sinusitis or postoperative maxillary cysts.

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