人工膜材料を利用した生体組織工学 Tissue Engineering Based on Biomaterial Membranes
Tissue engineering is one newly emerging biomedical form to assist the regeneration and repairing of body tissue or to substitute the biological functions of damaged organs by making use of living cells. However, the tissue regeneration cannot always be achieved only by giving the cells of high proliferation and differentiation potential to a body defect. To this end, it is key to artificially create a site suitable for regeneration induction at the body defect. This can be achieved by taking advantage of an artificial scaffold for cell proliferation and differentiation, growth factors, and their combinations. Tissue engineering involves the technology and methodology to assist the creation of site to induce the regeneration of tissue and organ by use of various biomaterials. Growth factor is often required to promote tissue regeneration while it can also induce angiogenesis which is effective in angiogenic therapy for ischemic disease or the supply of oxygen and nutrients to the cells transplanted for organ substitution. However, the biological effects cannot be always expected without the drug delivery system (DDS) of growth factor. This paper overviews recent research prospective of tissue engineering and emphasizes significance role of biomaterials in tissue engineering.
膜 27(6), 296-302, 2002-11-01
THE MEMBRANE SOCIETY OF JAPAN