Effect of Colforsin Daropate Hydrochloride after Pediatric Cardiac Surgery under Cardiopulmonary Bypass.

DOI 2 Citations 6 References
  • TAKEUCHI Mamoru
    Department of Anesthesiology and Resuscitology, Okayama University Medical School
  • MORITA Kiyoshi
    Department of Anesthesiology and Resuscitology, Okayama University Medical School
  • IWASAKI Tatsuo
    Department of Anesthesiology and Resuscitology, Okayama University Medical School
  • OE Katsunori
    Department of Anesthesiology and Resuscitology, Okayama University Medical School
  • TODA Yuichiro
    Department of Anesthesiology and Resuscitology, Okayama University Medical School
  • HIRAKAWA Masahisa
    Department of Anesthesiology and Resuscitology, Okayama University Medical School

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Other Title
  • 塩酸コルホルシンダロパート（アデール）の小児開心術への有用性

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Abstract

The differences in hemodynamic effects of colforsin daropate hydrochloride between the colforsin group and the control were evaluated by using a thermodilution catheter after cardiopulmonary bypass in pediatric cardiac surgery. In the colforsin group, the percent decrease of cardiac output was smaller than the control. A significant SVR reduction was obtained in the colforsin group. Colforsin can maintain cardiac output by decreasing systemic vascular resistance after pediatric cardiac surgery. There were no major side effects such as severe tachycardia and arrhythmia in our study. In conclusion, colforsin is a useful drug especially after pediatric cardiac surgery.

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