Hemodynamic Changes in Elderly and Younger Patients after Induction of Anesthesia with Thiopental. Detected by Ventriculo-arterial Coupling.

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  • 高齢者に対するチオペンタール麻酔導入が循環動態に与える影響　　Ｅｅｓ／Ｅａによる検討
  • Detected by Ventriculo-arterial Coupling
  • Ees/Eaによる検討

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Abstract

We assessed hemodynamic changes in elderly and younger patients after the induction of anesthesia with thiopental at 4.0mg•kg-1. After obtainning institutional approval and informed consent, 17 younger adults (<70yrs) and 10 elderly (>70yrs) patients were studied. All were free of significant cardiovascular disease. Before and after administration of thiopental, electrocardiograms, arterial pressure and phonocardiograms were continuously recorded for how long. Ventricuroarterial coupling (Ees/Ea) was calculated using the method described by Hayashi and Shigemi. In both groups, the mean arterial pressure (MAP) and Ees/Ea significantly decreased after administration of thiopental. However, the averages of the Ees/Ea after thiopental induction were within normal limits (1<Ees/Ea<2) in both groups. Our results suggest that mechanical efficiency is well-maintained in elderly patients after thiopental induction, whereas thiopental can decrease Ees/Ea and MAP.

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