書誌事項
- タイトル別名
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- Studies of urine protein components of orthostatic proteinuria. Changes of forced lordosis.
- —Changes of forced lordosis—
- ―腰椎前弯負荷試験による変動を中心に―
抄録
A total 24 cases with orthostatic proteinuria and 5 each of normal healthy subjects and chronic glomerulonephritis patients in clinically stable state were examined their changes of urine protein components before and after forced lordosis. In all of the analysis of urine protein components of resting and spot urines, the major component was albumin accompanied with small amount of alpha-1 acid glycoprotein and IgG globulin where no noticeable difference was observed among the above three clinical conditions. Only increases of the amounts of albumin were seen in the orthostatic proteinuria and chronic glomerulonephritis therefore, it was impossible to differentiation the two by means of analysis by spot urine. When forced lordosis was applied, there was no change of urinary protein excretion and components in healthy subjects before and after lordosis whereas in orthostatic proteinuria and chronic glomerulonephritis, increases of total protein excretion, especially that of albumin, were observed. Before and after the lordosis, no change of urine protein components were observed in chronic glomerulonephritis while in orthostatic proteinuria, along with a remarkable increase of protein excretion a transient low/non-selective proteinuria was observed after 30 minutes of lordosis as compared with the high selective proteinuria that was a charac-teristic change observed in all of the cases of orthostatic proteinuria. From this results thus above, when the cases that orthostatic proteinuria are suspected, it is useful for the confirmation of diagnosis of the disease, to perform, together with routine analysis, the forced lordosis and to analyse the urine protein components before and after lordosis.
収録刊行物
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- 日本腎臓学会誌
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日本腎臓学会誌 30 (1), 23-31, 1988
社団法人 日本腎臓学会