集中治療部におけるMethicillin‐resistant Staphylococcus aureus(MRSA)院内感染の追究  DNA解析を用いて

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  • DNA Analysis of Methicillin-resistant Staphylococcus aureus Nosocomial Outbreaks in ICU.
  • DNA解析を用いて

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The aging of the patient population and the advancement of medical science contribute to the increasing isolation frequency of methicillin-resistant Staphylococcus aureus (MRSA) from hospitalized patients. In Yamagata University Hospital, isolation of Staphylococcus aureus has also shown an annual increase, making up more than 20% of all isolates from clinical specimens, 70 to 80% of which are MRSA. Prevention of MRSA infection in ICU patients is especially important, because most patients are compromised hosts in whom MRSA infections tend to be refractory and severe. We conducted an investigation to examine the possibility of MRSA nosocomial outbreaks among patients admitted to the ICU from January 2000 to April 2001, using DNA analysis. Among the isolates, three cases were strongly suspected to be cross infections. Such sound epidemiological evidence was effective in improving infection control in the ICU.

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