Chronological Evaluation of the Onset of Histologically Confirmed Interstitial Pneumonia Associated with Polymyositis/dermatomyositis

• YANG Yu

  The Department of Rheumatology and Immunology, First Clinical College, China Medical University

• FUJITA Jiro

  The First Department of Internal Medicine, Kagawa Medical University

• TOKUDA Michiaki

  The First Department of Internal Medicine, Kagawa Medical University

• BANDOH Shuji

  The First Department of Internal Medicine, Kagawa Medical University

• ISHIDA Toshihiko

  The First Department of Internal Medicine, Kagawa Medical University

抄録

Objective The present study was designed to determine the chronological sequence of interstitial pneumonia, skin involvement, and muscle involvement associated with polymyositis/dermatomyositis (PM/DM).<br> Methods We examined our own cases of histologically confirmed interstitial pneumonia associated with PM/DM. In addition, a review of the literature was done to evaluate other cases of histologically confirmed interstitial pneumonia associated with PM/DM. Lung involvement was the first clinical symptom for all of our 8 patients.<br> Results Including the literature review and our 8 cases, there were 94 patients with PM/DM in whom interstitial pneumonia was histologically confirmed (36 PM, 50 DM, and 8 amyopathic DM). Chronological evaluation between the diagnosis of PM/DM and lung involvement demonstrated that most lung involvement occurred just before or just after the diagnosis of PM/DM. Interstitial pneumonia was preceded in 35 of 87 evaluable patients [21 cases with PM (61.8%), 14 cases with DM and amyopathic DM (40.2%)]. In 60 of 87 evaluable patients (69.0%), lung involvement occurred as a clinical manifestation at the diagnosis of PM/DM.<br> Conclusion The present data demonstrate that interstitial pneumonia was frequently the initial onset in patients with PM/DM.<br>(Internal Medicine 41:1135-1141, 2002)

収録刊行物

• Internal Medicine

  Internal Medicine 41 (12), 1135-1140, 2002

  一般社団法人 日本内科学会

キーワード

• surgical lung biopsy
• pathology
• pulmonary fibrosis

詳細情報

• CRID: 1390282679850103552
• NII論文ID: 10010582164
• NII書誌ID: AA10827774
• DOI: 10.2169/internalmedicine.41.1135
• COI: 1:STN:280:DC%2BD3s%2FhsVOmsQ%3D%3D
• ISSN: 13497235
• ISSN: 09182918
• NDL書誌ID: 6400176
• PubMed: 12521202
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6400176
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine1992/41/12/41_12_1135/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2003147944
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可