骨代謝指標から見た農村高齢者の健康状態  血清中オステオカルシンと尿中ミネラルについて

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タイトル別名
  • Evaluation of bone health in rural aged farmers by plasma osteocalcin and urinary mineral excretion.
  • コツ タイシャ シヒョウ カラ ミタ ノウソン コウレイシャ ノ ケンコウ ジョウタイ ケッセイ チュウ オステオカルシン ト ニョウ チュウ ミネラル ニ ツイテ

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抄録

To evaluate bone health of rural aged farmers, we investigated the serum levels of low- and high-carboxylated osteocalcins (Glu-OC and Gla-OC, respectively) and the urinary excretion of minerals, Ca, P, and Mg. Subjects were healthy aged farmers including 26 males and 18 females (7086 y). Both males and females were divided into three groups according to the serum Glu-OC levels. In the male subjects, the serum level of Gla-OC in the low Glu-OC group was significantly higher than those of the other groups (p<0.05). On the contrary, the serum Gla-OC level in the low Glu-OC group was significantly lower than those of the other groups in the female subjects (p< 0.05). The serum Glu-OC/Gla-OC ratio, which was indicative of reduction of OC carboxylation, in the high Glu-OC group was significantly higher than those of the other groups in both genders, and the females generally showed the significantly higher ratios compared to the males. On the other hand, the urinary concentration of Ca in the high Glu-OC group was significantly higher than that of the low Glu-OC group in the males. The similar tendency was observed also in the females. These results suggest that the serum Glu-OC and Gla-OC levels are useful indicators of bone health in rural aged farmers. Furthermore, it can be concluded that aged males should be more attentive to their bone health, as are females who are considered to be at the higher risk of osteoporosis.

収録刊行物

  • 民族衛生

    民族衛生 68 (5), 188-194, 2002

    日本民族衛生学会

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