低分子デキストラン標品の齲蝕抑制効果

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タイトル別名
  • Cariostatic Effect of Low Molecular Dextran

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The cariostatic effect of low molecular dextran was examined in vitro and in vivo experiments. The dextran preparation promoted insoluble glucan synthesis by glucosyltransferases of Streptococcus sobrinus 6715 from sucrose. However, sucrose-dependent adherence of the microorganism to glass surfaces was inhibited significantly in the presence of the dextran preparation. In SPF SD rats infected with S. sobrinus 6715, the dextran preparation significantly inhibited the caries induction and plaque accumulation. These results indicate that the dextran preparation could serve as an anti-cariogenic food additive.

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