小児の呼吸器感染症患者から分離されたＨａｅｍｏｐｈｉｌｕｓ　ｉｎｆｌｕｅｎｚａｅの注射用抗菌薬に対する薬剤感受性

• 坂田 宏

  旭川厚生病院小児科

書誌事項

タイトル別名

• Antimicrobial susceptibility of Haemophilits influenzae isolated from children with respiratory tract infection

抄録

We studied the minimum inhibitory concentrations (MICs) of ampicillin (ABPC), piperacillin (PIPC), cefotaxime (CTX), ceftriaxone (CTRX), meropenem (MEPM), and amoxicillin/clavulanic acid (AMPC/CVA) using Etest against 150 strains of Haemophilus influenzae isolated from upper nasopharyngealswabs in children with respiratory tract infection between August 2002 and March 2003. Subjects rangedin age from 1 month to 14 years. Of 150 isolates, β-lactamase-negative ABPC-susceptible (BLNAS) strains account for 60 (40.0%), β-lactamase-negative ABPC-resistant (BLNAR) strains for 84 (56.0%), β-lactamase-positive ABPC-resistant (BLPAR) strains for 5 (3.3%), and β-lactamase-positive AMPC/CVA-resistant (BLPACR) strains for 1 0.7 (%). Of 84 BLNAR, MICs to ABPC of 36 strains weremore than 4 μ/mL and those of 48 were more than 2 and less than 4 μ/mL. The MIC₉₀ was 0.25 μ/mL inCTRX, 0.25μ/mL in PIPC, 0.5 μ/mL in MEPM, 2μ/mL in CTX and 8μg/mL in ABPC. MIC90s ofBLNAS and BLNAR were 1.5 and 8 μ/mL in ABPC, 0.125 and 0.25μ/mL in PIPC, 1.5 and 8μg/mL inCTX, 0.125 and 0.38 μ/mL in CTRX, and 0.19 and 0.5 μ/mL in MEPM.

収録刊行物

• 日本化学療法学会雑誌

  日本化学療法学会雑誌 51 (9), 569-573, 2003

  公益社団法人 日本化学療法学会

キーワード

• Haemophilus influenzae
• susceptibility
• β-actamase negative ampicillin resistant
• respiratory tract infection
• child

詳細情報

• CRID: 1390282681260938496
• NII論文ID: 10011693839
• NII書誌ID: AN10472127
• DOI: 10.11250/chemotherapy1995.51.569
• ISSN: 18845886
• ISSN: 13407007
• Web Site: https://search.jamas.or.jp/link/ui/2004084291
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可