Improved Detectability with a Polymer-based Trapping Device in Rapid HPLC Analysis for Ultra-low Levels of Bisphenol A (BPA) in Environmental Samples

• WATABE Yoshiyuki

  Department of Polymer Science & Engineering, Kyoto Institute of Technology

• KONDO Takuya

  Endocrine Disrupters Research Laboratory, National Institute for Environmental Studies

• IMAI Hiroe

  Endocrine Disrupters Research Laboratory, National Institute for Environmental Studies

• MORITA Masatoshi

  Endocrine Disrupters Research Laboratory, National Institute for Environmental Studies

• TANAKA Nobuo

  Department of Polymer Science & Engineering, Kyoto Institute of Technology

• HAGINAKA Jun

  Faculty of Pharmaceutical Sciences, Mukogawa Women’s University

• HOSOYA Ken

  Department of Polymer Science & Engineering, Kyoto Institute of Technology

抄録

A new high-performance liquid chromatography (HPLC) method has been developed to detect ultra-low concentrations of bisphenol-A (BPA) (below 1 ng/L (ppt)) using column switching electrochemical detection (ECD). The results were superior to those obtained from manual pretreatment procedure with membrane stationary phase. BPA is inherently ubiquitous in the environment, including tools and solvents used for its analysis; to obtain meaningful results, therefore, the concentration of the overall BPA contamination must be below the detection limit for BPA using the analytical system. Therefore, purified water for preparing the standard BPA solution must be filtered with a hydrophobic membrane to suppress BPA background levels of contamination. In addition, we investigated methods for effectively preserving environmental water containing BPA. The addition of a small amount of ethylenediaminetetraacetic acid (EDTA) provided good recovery even after overnight storage. By employing these precautionary measures and procedures to reduce BPA contamination from the analytical procedure, we could accurately determine 1 - 10 ppt of BPA in environmental water samples using a column switching HPLC system.

収録刊行物

• Analytical Sciences

  Analytical Sciences 20 (1), 133-137, 2004

  社団法人 日本分析化学会

キーワード

• Analytical Chemistry

詳細情報

• CRID: 1390282679233829760
• NII論文ID: 130004440834
• NII論文ID: 10011942659
• NII書誌ID: AA10500785
• DOI: 10.2116/analsci.20.133
• COI: 1:CAS:528:DC%2BD2cXmvFWitQ%3D%3D
• ISSN: 13482246
• ISSN: 09106340
• NDL書誌ID: 6810227
• PubMed: 14753271
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6810227
• Web Site: https://link.springer.com/content/pdf/10.2116/analsci.20.133.pdf
• Web Site: https://link.springer.com/article/10.2116/analsci.20.133/fulltext.html
• Web Site: http://www.jstage.jst.go.jp/article/analsci/20/1/20_1_133/_pdf
• 本文言語コード: en
• データソース種別:
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  • NDL
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