Elevated Concentrations of Soluble IL-2 Receptor in both Bronchoalveolar Lavage Fluid and Serum in a Patient with BOOP
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- Matsuno Osamu
- Department of Internal Medicine, Usuki Cosmos Hospital
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- Okubo Fumiko
- Department of Internal Medicine, Usuki Cosmos Hospital
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- Masutomo Kazuhiro
- Department of Internal Medicine, Usuki Cosmos Hospital
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- Yoshida Fumio
- Department of Internal Medicine, Usuki Cosmos Hospital
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- Okubo Tosiyuki
- Department of Immunology and Allergy, Oita Medical University
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- Miyazaki Eishi
- Department of Immunology and Allergy, Oita Medical University
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- Kumamoto Tosihide
- Department of Immunology and Allergy, Oita Medical University
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Abstract
Activated soluble IL-2 receptor (sIL-2R) levels are elevated in a variety of diseases associated with T-cell activation. There are no reports of sIL-2R elevations in broncholitis obliterans organizing pneumonia/cryptogenic organizing pneumonia (BOOP/COP), although activated T cells are increased in BOOP/COP. We present a patient with BOOP/COP with an elevated concentration of soluble IL-2 receptors in both serum and bronchoalveolar lavage fluid. Concomitant resolution of the high serum sIL-2R and the roentogenographic findings after steroid treatment suggested that serum sIL-2R levels increase in response to a localized lymphocytic inflammatory reaction in the lung.
Journal
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 201 (1), 61-65, 2003
Tohoku University Medical Press
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Keywords
Details 詳細情報について
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- CRID
- 1390001204240686976
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- NII Article ID
- 130004459277
- 10011991034
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- NII Book ID
- AA00863920
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- COI
- 1:STN:280:DC%2BD3srjtFSruw%3D%3D
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- ISSN
- 13493329
- 00408727
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- PubMed
- 14609262
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- Text Lang
- en
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- Data Source
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed
