Gene-Based Deafness Research: Ion Transport and Hearing

• Ikeda Katsuhisa

  Department of Otorhinolaryngology, Juntendo University School of Medicine

Abstract

The cochlea is a sensory organ that converts physical (sound) stimulation into electrical signals. This process is fundamentally and substantially based upon the ion transport system. Here, I summarize the physiological and molecular biological aspects of transporters, channels and receptors expressed in the cochlea. With reference to these findings, recent advances in genetic research on hereditary deafness are discussed.

Journal

• The Tohoku Journal of Experimental Medicine

  The Tohoku Journal of Experimental Medicine 202 (1), 1-11, 2004

  Tohoku University Medical Press

Keywords

• deafness
• ion transport
• hereditary deafness
• DNA

Details

• CRID: 1390001204239528704
• NII Article ID: 10011991694
• NII Book ID: AA00863920
• DOI: 10.1620/tjem.202.1
• COI: 1:CAS:528:DC%2BD2cXhtFGntrw%3D
• ISSN: 13493329
• ISSN: 00408727
• PubMed: 14738319
• Web Site: http://www.jstage.jst.go.jp/article/tjem/202/1/202_1_1/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2005139530
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed