超原子価ヨウ素試薬を用いる水中での新規酸化反応の開発

• 当麻 博文

  大阪大学大学院薬学研究科分子合成化学分野

• 北 泰行

  大阪大学大学院薬学研究科分子合成化学分野

書誌事項

タイトル別名

• Development of Novel Oxidation Reactions in Water Using Hypervalent Iodine Reagents
• チョウゲンシカ ヨウソ シヤク オ モチイル スイチュウ デ ノ シンキ サンカ ハンノウ ノ カイハツ

抄録

Various aqueous oxidation reactions have been developed since economic and environmental concerns encourage the use of water as a reaction medium. Hypervalent iodine compounds have been used extensively in organic synthesis due to not only low toxicity, ready availability, and easy handling, but also reactivities similar to those of heavy metal reagents or anodic oxidation. However, most of the hypervalent iodine oxidation reactions have been carried out only in limited organic solvents because both the solubility and the reactivity of organo-iodine (III or V) compounds have remarkably been decreased in water. In this article, we report novel activation methods of hypervalent iodine species in water and their application to the development of environmentally benign oxidation reactions using polymer-supported iodine (III) reagents. Furthermore, these methods enabled us to replace iodine (V) reagents, such as Dess-Martin periodinane (DMP) and ο-iodoxybenzoic acid (IBX) with much safer (non-explosive) and commercially available iodine (III) reagents.

収録刊行物

• 有機合成化学協会誌

  有機合成化学協会誌 62 (2), 116-127, 2004

  公益社団法人 有機合成化学協会

キーワード

• hypervalent iodine reagent
• oxidation
• water
• polymer-supported reagent
• environmentally benign reaction

詳細情報

• CRID: 1390001205312602624
• NII論文ID: 10012048986
• NII書誌ID: AN0024521X
• DOI: 10.5059/yukigoseikyokaishi.62.116
• COI: 1:CAS:528:DC%2BD2cXhtlGisro%3D
• ISSN: 18836526
• ISSN: 00379980
• ISSN: http://id.crossref.org/issn/00379980
• NDL書誌ID: 6848804
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6848804
• 本文言語コード: ja
• データソース種別:
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  • NDL
  • Crossref
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  • KAKEN
• 抄録ライセンスフラグ: 使用不可