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- 河瀬 雅美
- 城西大学薬学部
書誌事項
- タイトル別名
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- Synthetic and Medicinal Chemistry of Trifluoromethyl Ketones.
- トリフルオロメチル ケトンルイ ノ シンキ ゴウセイホウ ノ カイハツ ト ソウヤク
この論文をさがす
抄録
Trifluoromethyl ketones (TFMKs) are of considerable current interest due to their importance as synthetic intermediates and their ability to act as potent enzyme inhibitors. This article briefly reviews recent ten-years progress in the chemistry of TFMKs and describes our studies on the new method for the preparation of TFMKs. Furthermore, screenings of a variety of structurally diverse TFMKs, with the view to identify a lead TFMK with anti-Helicobacter pylori, antimicrobial or apoptosis-inducing and -inhibitory activities are shown. These studies led to the identification of several TFMKs as a lead molecule.
収録刊行物
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- 有機合成化学協会誌
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有機合成化学協会誌 59 (8), 755-765, 2001
公益社団法人 有機合成化学協会
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詳細情報 詳細情報について
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- CRID
- 1390001205276651392
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- NII論文ID
- 10012287490
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- NII書誌ID
- AN0024521X
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- COI
- 1:CAS:528:DC%2BD3MXmt1Cnu7Y%3D
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- ISSN
- 18836526
- 00379980
- http://id.crossref.org/issn/00379980
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- NDL書誌ID
- 5867077
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可