Predictive factor of cervical lymph node metastasis in squamous cell carcinoma of the tongue

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  • 舌扁平上皮癌における頸部リンパ節への転移予測因子について

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Abstract

The relationship between delayed cervical lymph node metastasis and clinico-pathological prognostic factors was retrospectively investigated in 57 patients with NO in squamous cell carcinoma of the to tongue who underwent surgical treatment from 1981 to 1996.<BR>1. Delayed cervical lymph node metastases developed in 11 of 57 patients (19.3%) within 5 years. Factors significantly associated with the development of delayed cervical lymph node metastases were tumor size, tumor thickness, vasucular permeation, and histological grading of malignancy.<BR>2. The incidence of delayed cervical lymph node metastasis increased markedly when the tumor thickness was over 4 mm, the tumor size was over 30 mm, and histological malignancy point was over 17 points.<BR>Thus, these results demonstrated that concervative neck dissection is indicated in patients with N0 in carcinoma of the tongue whose tumors are >30 mm in size, >4 mm in thickness, and >17 points in histological malignancy point.

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