A Man with Interstitial Pneumonia Due to Propylthiouracil

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著者

    • Ohwada Rina OHWADA Rina
    • Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, School of Medicine
    • Kato Keiko KATO Keiko
    • Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, School of Medicine
    • ISOZAKI Osamu
    • Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, School of Medicine
    • HOTTA Mari
    • Health Services Center, National Graduate Institute For Policy Studies
    • ONO Masami
    • Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, School of Medicine
    • TAKANO Kazue
    • Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University, School of Medicine

抄録

A 50-year-old Japanese man with Grave's disease had been taking propylthiouracil (PTU) for 10 years prior to the diagnosis of pneumonia. He noticed dyspnea on exertion and had a dry cough for at least 2 years and then suddenly developed high fever and dyspnea at rest. Clinical symptoms, chest radiographs, chest computed tomography and lung function revealed interstitial pneumonia. The symptoms were completely resolved after withdrawal of PTU, and consequently he was diagnosed with PTU-induced interstitial pneumonia. He also showed moderate myeloperoxidase (MPO)- antineutrophil cytoplasmic antibody (ANCA) positivity without any signs of vasculitis before as well as after PTU withdrawal. Although PTU-induced interstitial pneumonia is quite rare, with only 3 cases, including the present patient, so far reported, respiratory involvement should be considered in patients treated with PTU.<br>(Internal Medicine 42: 1026-1030, 2003)

収録刊行物

  • Internal medicine

    Internal medicine 42(10), 1026-1030, 2003-10-01

    The Japanese Society of Internal Medicine

参考文献:  11件中 1-11件 を表示

被引用文献:  2件中 1-2件 を表示

各種コード

  • NII論文ID(NAID)
    10012457374
  • NII書誌ID(NCID)
    AA10827774
  • 本文言語コード
    ENG
  • 資料種別
    NOT
  • ISSN
    09182918
  • NDL 記事登録ID
    6721631
  • NDL 雑誌分類
    ZS21(科学技術--医学--内科学)
  • NDL 請求記号
    Z53-M398
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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