遺伝性血管神経浮腫を有する患者の歯科治療経験

  • 坂田 康彰
    三井記念病院歯科・歯科口腔外科 東京大学医学部附属病院顎口腔外科・歯科矯正歯科
  • 西川 久美子
    東京大学医学部附属病院顎口腔外科・歯科矯正歯科
  • 森 良之
    東京大学医学部附属病院顎口腔外科・歯科矯正歯科
  • 坂本 泰宏
    三井記念病院歯科・歯科口腔外科
  • 津山 泰彦
    三井記念病院歯科・歯科口腔外科
  • 高戸 毅
    東京大学医学部附属病院顎口腔外科・歯科矯正歯科

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  • Experience with dental treatment in a patient with hereditary angioneurotic edema (HANE)

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The surgical treatment of a patient with hereditary angioneurotic edema (BANE) is described in the present report. HANE is an autosomal dominant hereditary disease that causes acute and local submucocutaneous edema. It is a very rare disease in Japan and has been reported in only 20 femilies.<BR>The subject was a 24-year-old woman with right upper pericoronitis who had been given a diagnosis of HANE at the age of 13 years. Patients with HANE often have fatal laryngeal edema during dental treatment such as extraction of teeth. Therefore, our patient received ginigivectomy after being hospitalized. Postoperatively, she had mild respiratory distress, but it was controlled by intravenous drip infusion of C 1 esterase inhibitor. When treating patients with HANE, we should take sufficient measures to avoid the development of edema, even when treatment is minimally invasive. Furthermore, sufficient preparation for urgent tracheotomy is necessary owing to the risk of laryngeal edema.

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