p53タンパクが陽性であった verrucous carcinoma の1例 A case of p53 protein positive verrucous carcinoma

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著者

    • 木下 智 KINOSHITA Satoshi
    • 大阪歯科大学口腔外科学第1講座 First Department of Oral and Maxillofacial Surgery, Osaka Dental University
    • 久保 誼修 KUBO Yoshinobu
    • 大阪歯科大学口腔外科学第1講座 First Department of Oral and Maxillofacial Surgery, Osaka Dental University
    • 中尾 有里 NAKAO Yuri
    • 大阪歯科大学口腔外科学第1講座 First Department of Oral and Maxillofacial Surgery, Osaka Dental University
    • 渡邉 岳 WATANABE Gaku
    • 大阪歯科大学口腔外科学第1講座 First Department of Oral and Maxillofacial Surgery, Osaka Dental University
    • 虫本 浩三 MUSHIMOTO Kozo
    • 大阪歯科大学口腔外科学第1講座 First Department of Oral and Maxillofacial Surgery, Osaka Dental University

抄録

We describe our experience with a case of verrucous carcinoma arising in the upper residual ridge. A 71-year-old woman presented with a gingival swelling. On examination, we detected a granular mass in the 7-2 I region and leukoplakia lesions with an irregular surface in the 2+2 region. Radiography showed slight radiolucency of alveolar bone at the 7-2 region. Two biopsies of the mass showed papillomas. The patient underwent excision of the tumor under general anesthesia. The histopathologic diagnosis was verrucous carcinoma. We detected a tumor suppressor gene product, p53. This finding suggested that overexpression of p53 was involved in carcinogenesis. As of more than 5 years after operation, we have found no evidence of recurrence or metastasis.

収録刊行物

  • 日本口腔外科学会雑誌

    日本口腔外科学会雑誌 49(9), 533-536, 2003-09-20

    Japanese Society of Oral and Maxillofacial Surgeons

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各種コード

  • NII論文ID(NAID)
    10012629899
  • NII書誌ID(NCID)
    AN00189163
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00215163
  • データ提供元
    CJP書誌  J-STAGE 
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