<I>Development of Reaction Using Imines as a Radical Acceptor and Its Stereocontrol</I>

• Miyabe Hideto

  Kobe Pharmaceutical University

• Naito Takeaki

  Kobe Pharmaceutical University

Bibliographic Information

Other Title

• イミン類をラジカル受容体とした反応の開発とその立体制御
• イミンルイ オ ラジカル ジュヨウタイ ト シタ ハンノウ ノ カイハツ ト ソノ リッタイ セイギョ

Abstract

This review summarizes the recent progress in the field of radical reaction of imine derivatives, and focuses on the new carbon-carbon bond constructing-methods especially based on intermolecular carbon radical addition to imine derivatives. Among the wide range of radical acceptors containing a carbon-nitrogen double bond, it was revealed that the oxime ethers were excellent radical acceptors, and a lot of studies have been explored by using oxime ethers. Reactivity of imine derivatives and possible reaction pathways have also been presented. The reaction was extended to one-pot and/or multi-component reactions. Moreover, a high degree of stereocontrol in reaction of acyclic and cyclic imine derivatives was achieved by using triethylborane and diethylzinc.

Journal

• Journal of Synthetic Organic Chemistry, Japan

  Journal of Synthetic Organic Chemistry, Japan 59 (1), 33-39, 2001

  The Society of Synthetic Organic Chemistry, Japan

Keywords

• radical
• imine
• oxime ether
• amino acid
• triethylborane
• diethylzinc
• one-pot
• multicomponent
• asymmetric synthesis
• solid-phase

Details

• CRID: 1390001205277794304
• NII Article ID: 10012766942
• NII Book ID: AN0024521X
• DOI: 10.5059/yukigoseikyokaishi.59.33
• COI: 1:CAS:528:DC%2BD3MXhtFWlsr0%3D
• ISSN: 18836526
• ISSN: 00379980
• ISSN: http://id.crossref.org/issn/00379980
• NDL BIB ID: 5632723
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I5632723
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed