Change for aging of serum alkaline phosphatase isoenzyme in Korean native goat.

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  • 韓国在来ヤギにおける血清アルカリ性ホスファターゼ・アイソエンザイムの加齢変化
  • カンコク ザイライ ヤギ ニ オケル ケッセイ アルカリセイ ホスファターゼ アイソエンザイム ノ カレイヘンカ

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Abstract

Alkaline phosphatase (ALP) in serum of Korean native goat is composed of isoenzymes derived from intestine, bone and liver. From the band patterns of polyacrylamide gel electrophoresis (PAGE), the ALP organ type was classified into five patterns. The F type band detected by starch gel electrophoresis (SGE) originated from liver ALP. As the ALP type of goat serum has been classified into F type and 0/0 type by SGE, the F and 0/0 types could be classified respectively into F/F or F/0 types and F/0 or 0/0 types by PAGE (AlkPhor SYSTEM). The ALP types changed by aging. The 0/0 type individual, which was composed of only bone ALP, was undetectable in individuals over three years old. This suggests that skeletogeny is completed by the age of three in Korean native goat. As 0/0 type individuals died before three years old, this may indicate that liver ALP is necessary for their survival beyond three years of age. The Korean native goat population was characteristically divided into a high (over 500IU/l) and low (under 500IU/l) group by ALP activity value.

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