上咽頭原発悪性黒色腫例 A Case Report of Primary Malignant Melanoma of the Nasopharynx

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Primary malignant melanoma of the nasopharynx is a rare disease with poor prognosis. There has been no established treatment for the disease.<br>We report herein a case of a 75-year old man, who was referred with hearing impairment and nasal obstruction. Clinical examination demonstrated left middle ear effusion and nasopharyngeal mass. The histological examination indicated malignant melanoma. Magnetic resonance imaging (MRI) showed a gadolinium-enhanced mass on the left side of nasopharynx. Imaging studies could not detect distant metastasis. The patient received combined chemotherapy with DAV treatment (DTIC+ACNU+VCR), but there was no response. Intratumoral administration of Interferon-beta inhibited tumor growth and X-knife was also effective in significantly decreasing tumor size. These therapies may be helpful in the local treatment of malignant melanoma, thus improving the patient's quality of life.

収録刊行物

  • 耳鼻咽喉科臨床

    耳鼻咽喉科臨床 97(4), 307-312, 2004-04-01

    The Society of Practical Otolaryngology

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各種コード

  • NII論文ID(NAID)
    10012846045
  • NII書誌ID(NCID)
    AN00107089
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00326313
  • NDL 記事登録ID
    6909676
  • NDL 雑誌分類
    ZS43(科学技術--医学--耳鼻咽喉科学)
  • NDL 請求記号
    Z19-421
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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