Stably-dispersed and Surface-functional Bionanoparticles Prepared by Self-assembling Amphipathic Polymers of Hydrophilic Poly(γ-glutamic acid) Bearing Hydrophobic Amino Acids

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著者

    • MATSUSAKI Michiya
    • Department of Nanostructured and Advanced Materials, Graduate School of Science and Engineering, Kagoshima University
    • HIWATARI Ken-ichiro
    • Department of Nanostructured and Advanced Materials, Graduate School of Science and Engineering, Kagoshima University
    • HIGASHI Mariko
    • Department of Nanostructured and Advanced Materials, Graduate School of Science and Engineering, Kagoshima University
    • KANEKO Tatsuo
    • Department of Nanostructured and Advanced Materials, Graduate School of Science and Engineering, Kagoshima University
    • AKASHI Mitsuru
    • Department of Nanostructured and Advanced Materials, Graduate School of Science and Engineering, Kagoshima University

抄録

Surface-functional bionanoparticles were prepared by self-assembling amphipathic poly(γ-glutamic acid) derivatives with a hydrophilic backbone and hydrophobic phenylalanine and leucine side groups. Poly(γ-glutamic acid) bearing phenylalanine nanospheres exhibited excellent water-dispersibility, surface functionality and appropriate size (200 nm) for medical use. Additive PEG conjugation assisted nanoparticle formation of leucine-grafted poly(γ-glutamic acid).

収録刊行物

  • Chemistry letters

    Chemistry letters 33(4), 398-399, 2004-04-05

    The Chemical Society of Japan

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各種コード

  • NII論文ID(NAID)
    10012846950
  • NII書誌ID(NCID)
    AA00603318
  • 本文言語コード
    ENG
  • 資料種別
    SHO
  • ISSN
    03667022
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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