Synthesis of Model Compound Containing an Indole Spiro-β-lactam Moiety with Vinylchloride in Chartellines

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Author(s)

    • NISHIKAWA Toshio
    • Laboratory of Organic Chemistry, Graduate School of Bioagricultural Science, Nagoya University
    • KAJII Shigeo
    • Laboratory of Organic Chemistry, Graduate School of Bioagricultural Science, Nagoya University
    • ISOBE Minoru
    • Laboratory of Organic Chemistry, Graduate School of Bioagricultural Science, Nagoya University

Abstract

A model compound containing an indole β-lactam moiety bearing vinylchloride in chartellines was synthesized from the Mannich reaction of isatin imine with ketene silyl acetal, β-lactam formation of the resulting β-amino ester, and copper(I)-mediated coupling with (<I>E</I>)-α-chloro-β-iodostyrene.

Journal

  • Chemistry Letters

    Chemistry Letters 33(4), 440-441, 2004-04-05

    The Chemical Society of Japan

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Codes

  • NII Article ID (NAID)
    10012847264
  • NII NACSIS-CAT ID (NCID)
    AA00603318
  • Text Lang
    ENG
  • Article Type
    SHO
  • ISSN
    03667022
  • Data Source
    CJP  J-STAGE 
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