Synthesis of Model Compound Containing an Indole Spiro-β-lactam Moiety with Vinylchloride in Chartellines

  • Nishikawa Toshio
    Laboratory of Organic Chemistry, Graduate School of Bioagricultural Science, Nagoya University PRESTO, Japan Science and Technology Agency
  • Kajii Shigeo
    Laboratory of Organic Chemistry, Graduate School of Bioagricultural Science, Nagoya University
  • Isobe Minoru
    Laboratory of Organic Chemistry, Graduate School of Bioagricultural Science, Nagoya University

書誌事項

タイトル別名
  • Synthesis of Model Compound Containing an Indole Spiro-.BETA.-lactam Moiety with Vinylchloride in Chartellines

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抄録

A model compound containing an indole β-lactam moiety bearing vinylchloride in chartellines was synthesized from the Mannich reaction of isatin imine with ketene silyl acetal, β-lactam formation of the resulting β-amino ester, and copper(I)-mediated coupling with (E)-α-chloro-β-iodostyrene.

収録刊行物

  • Chemistry Letters

    Chemistry Letters 33 (4), 440-441, 2004

    公益社団法人 日本化学会

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