転移巣に横紋筋成分の出現を認めた食道の「いわゆる癌肉腫」の1例

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  • A CASE OF SO-CALLED CARCINOSARCOMA OF THE ESOPHAGUS WITH RHABDOMYOSARCOMATOUS CHANGES IN THE CARDIAC LYMPH NODES METASTASIS

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A 62-year-old man presented with dysphagia and chest discomfort. Esophagogram and upper digestive tract endoscopy revealed a polypoid mass, 8.0-cm in size, in the lower intrathracic and abdominal esophagus. We diagnosed pseudosarcomatous squamous cell carcinoma on histology and treated with a subtotal esophagectomy. Histologically, most of the tumor was composed of spindle cells with mitosis. And squamous cell carcinoma presented focally at the base of the polypoid tumor. Immunohistochemically, spindle cells were stained with vimentin and partially stained with cytokeratin. Squamous cell carcinoma was stained with cytokeratin. These findings indicated that the tumor should be designated as so-called carcinosarcoma, according to the classification of carcinosarcoma recommended by the Japanese Society for Esophageal Disease. And rhab-domyosarcomatous cells were found in the sarcomatous portion of cardiac lymph nodes metastasis.

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