Histologically Low-grade Fibrosarcoma Occurring at Zygomaticofacial Area in an American Cocker Spaniel

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  • アメリカンコッカスパニエルの頬部に発生した組織学的低グレード線維肉腫の1例
  • アメリカン コッカスパニエル ノ キョウブ ニ ハッセイ シタ ソシキガクテキ テイグレード センイ ニクシュ ノ 1レイ

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Abstract

A 7-year-old American cocker spaniel was presented for evaluation of a subcutaneous mass at right zygomaticofacial area. Histopathological examination of the biopsy sample indicated that the mass lesion was fibroma. The mass rapidly grew up twice in size for 45 days after the first admission and was removed surgically. The histological appearance of the mass was almost in conformity with that of the first biopsy sample. However, recurrent tumor gradually invaded into the orbital, nasal, and oral area with bone absorption. The dog was euthanized 9 months after the first admission. Histpathologically, the recurrent tumor had higher cellularity and atipia, and had larger number of immunopositive cells for proliferate-cell nuclear antigen when compared to the original tumor. Based on these clinicopathological findings, the tumor was considered as histologically low-grade fibrosarcoma.

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