TEMPORAL BONE PATHOLOGY IN WEGENER'S GRANULOMATOSIS

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This study aimed to demonstrate the temporal bone histopathology of two cases of Wegener's granulomatosis in which the initial symptoms were profound hearing loss and facial nerve palsy respectively.<br>The first case, a woman of 44, suffered profound hearing loss which was remarkably improved by steroid and cyclophosphamide treatment for a time, and which seemed to be caused by invasion from granulation tissue filled in the tympanic cavity. The second case was a 61-year-old woman presenting with the facial nerve palsy. The bony canal of the horizontal portion of the facial nerve was destroyed due to granulation tissue which filled in the tympanic cavity, and granulomatous involvement was observed in the facial nerve. Wegener's granulomatosis can involve the middle ear and/or inner ear, causing hearing loss of conductive, mixed or sensorineural type. Pathogenesis of facial nerve palsy seems to be related to Wegener's granulomatous involvement of facial nerve, because the facial nerve palsy also resolved by using steroid and cyclophosphamide.

収録刊行物

  • Fukushima journal of medical science

    Fukushima journal of medical science 46(1), 31-39, 2000-12-01

    福島医学会

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被引用文献:  2件中 1-2件 を表示

各種コード

  • NII論文ID(NAID)
    10013002806
  • NII書誌ID(NCID)
    AA0065246X
  • 本文言語コード
    ENG
  • 資料種別
    NOT
  • ISSN
    00162590
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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