Sesamol Induces Apoptosis in Human Lymphoid Leukemia Molt 4B Cells

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抄録

The exposure of human lymphoid leukemia Molt 4B cells to sesamol, a component of sesame oil led to both growth inhibition and the induction of apoptosis. Morphological change showing apoptotic bodies was observed in the cells treated with sesamol. The fragmentation of DNA by sesamol to oligonucleosomal-sized fragments that are characteristics of apoptosis was observed to be concentration- and time-dependent. On the other hand, in the sesamol-treated normal human lymphocytes morphological change and DNA fragmentation were not observed at all. These findings suggest that growth inhibition of Molt 4B cells by sesamol results from the induction of apoptosis in the cells.

収録刊行物

  • Food science and technology research

    Food science and technology research 6(3), 201-203, 2000-08-01

    Japanese Society for Food Science and Technology

参考文献:  8件中 1-8件 を表示

被引用文献:  2件中 1-2件 を表示

各種コード

  • NII論文ID(NAID)
    10013008552
  • NII書誌ID(NCID)
    AA11320122
  • 本文言語コード
    ENG
  • 資料種別
    NOT
  • ISSN
    13446606
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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