Single-molecule measurement and imaging

DOI Web Site 71 References
  • ISHIKAWA Mitsuru
    Single-Molecule Bioanalysis Laboratory, National Institute of Advanced Industrial Science and Technology
  • FUTAMATA Masayuki
    Nanoarchitectonics Research Center, National Institute of Advanced Industrial Science and Technology

Bibliographic Information

Other Title
  • 単一分子計測・イメージング技術
  • タンイツ ブンシ ケイソク イメージング ギジュツ

Search this article

Abstract

<p>We overview the recent development of single-molecule measurement based on light microscopy and spectroscopy. A key advantage of single-molecule measurement over ensemble measurement is distinct in revealing characteristics of individual molecules that are hidden under ensembles. Several topics are presented in light of this advantage. Also, another advantage of single-molecule measurement is emphasized in an application of chemical analysis, particularly in single-molecule DNA sequencing. Finally, special attention is paid to the use of surface-enhanced Raman spectroscopy, which is free from labeling target analytes, as a key tool of single-molecule chemical analysis.</p>

Journal

  • Oyo Buturi

    Oyo Buturi 73 (6), 711-724, 2004-06-10

    The Japan Society of Applied Physics

References(71)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top