体内環境維持機構としての上皮輸送とその構成因子 Epithelial Transport as a Mechanism of Internal Homeostasis and its Elements

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著者

    • 佐々木 成 SASAKI Sei
    • 東京医科歯科大学 大学院腎臓内科学 Department of Nephrology, Graduate School, Tokyo Medical and Dental University

抄録

Water and solutes transport in epithelial tissues is an important mechanism for maintenance of the homeostasis of internal environment; volume and composition of extracellular fluid. Molecular technologies and advancement of the genome projects have identified plenty of membrane proteins that mediate epithelial transport. Membrane transport proteins can be classified into channel, solute carrier, ABC transporter, and pump. Each of the categories includes many families; for example, solute carrier consists of 43 families and 298 genes in human. Reflecting the importance of transport proteins, many hereditary diseases are proved to be due to gene mutations of transport proteins. Cross talk between clinical information and basic cell molecular biology data of these hereditary diseases will further advance our knowledge of transport proteins and their diseases.

収録刊行物

  • 膜 29(3), 148-153, 2004-05-01

    日本膜学会

各種コード

  • NII論文ID(NAID)
    10013114397
  • NII書誌ID(NCID)
    AN0023215X
  • 本文言語コード
    JPN
  • 資料種別
    REV
  • ISSN
    03851036
  • NDL 記事登録ID
    6970901
  • NDL 雑誌分類
    ZR2(科学技術--生物学--生化学)
  • NDL 請求記号
    Z18-1127
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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