Metofluthrin: A Potent New Synthetic Pyrethroid with High Vapor Activity against Mosquitoes

• UJIHARA Kazuya

  Agricultural Chemicals Research Laboratory, Sumitomo Chemical Co., Ltd.

• MORI Tatsuya

  Agricultural Chemicals Research Laboratory, Sumitomo Chemical Co., Ltd.

• IWASAKI Tomonori

  Agricultural Chemicals Research Laboratory, Sumitomo Chemical Co., Ltd.

• SUGANO Masayo

  Agricultural Chemicals Research Laboratory, Sumitomo Chemical Co., Ltd.

• SHONO Yoshinori

  Agricultural Chemicals Research Laboratory, Sumitomo Chemical Co., Ltd.

• MATSUO Noritada

  Agricultural Chemicals Research Laboratory, Sumitomo Chemical Co., Ltd.

Abstract

  (1R)-trans-Norchrysanthemic acid fluorobenzyl esters are synthesized and their structure-activity relationships are discussed. These esters show outstanding insecticidal activity against mosquitoes. In particular, the 2,3,5,6-tetrafluoro-4-methoxymethylbenzyl analog (metofluthrin) exhibits the highest potency, being approximately forty times as potent as d-allethrin in a mosquito coil formulation when tested against southern house mosquitoes (Culex quinquefasciatus). Metofluthrin also exhibits a significant vapor action at room temperature.

Journal

• Bioscience, Biotechnology, and Biochemistry

  Bioscience, Biotechnology, and Biochemistry 68 (1), 170-174, 2004

  Japan Society for Bioscience, Biotechnology, and Agrochemistry

Keywords

• metofluthrin
• norchrysanthemic acid
• vapor action
• mosquito coil
• fan vaporizer

Details

• CRID: 1390282681451414656
• NII Article ID: 10013141223
• NII Book ID: AA10824164
• DOI: 10.1271/bbb.68.170
• COI: 1:CAS:528:DC%2BD2cXhtFKgt7o%3D
• ISSN: 13476947
• ISSN: 09168451
• ISSN: http://id.crossref.org/issn/00032697
• NDL BIB ID: 6832686
• PubMed: 14745180
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6832686
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.68.170
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed