Sjogren's Syndrome Complicated with Autoimmune Hepatitis and Antiphospholipid Antibody Syndrome

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A 56-year-old Japanese female simultaneously developed thrombocytopenia, sicca symptoms, and an elevation of transaminase. Antiphospholipid antibodies were detected in her serum. The presence of anti-SS-A antibodies in the serum and sialectasis, disclosed by sialography, suggested the presence of primary Sjögren's syndrome (SjS). The laboratory data and the biopsy of the liver showed compatible findings with autoimmune hepatitis (AIH). Thrombocytopenia and liver dysfunction satisfactorily responded to corticosteroid. To our knowledge, this is the first reported case of SjS with AIH and antiphospholipid antibody syndrome (APAS). Analysis of serum cytokine levels showed a predominance of Th0-Th1 response, which is not compatible with AIH, in this complicated autoimmune state.<br>(Internal Medicine 39: 73-76, 2000)

収録刊行物

  • Internal medicine

    Internal medicine 39(1), 73-76, 2000-01-01

    一般社団法人 日本内科学会

参考文献:  11件中 1-11件 を表示

被引用文献:  4件中 1-4件 を表示

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各種コード

  • NII論文ID(NAID)
    10013261187
  • NII書誌ID(NCID)
    AA10827774
  • 本文言語コード
    ENG
  • 資料種別
    NOT
  • ISSN
    09182918
  • NDL 記事登録ID
    4965454
  • NDL 雑誌分類
    ZS21(科学技術--医学--内科学)
  • NDL 請求記号
    Z53-M398
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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