Clinical Effect of Dentifrice Containing Sodium Ascorbate on Periodontitis
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- Hisano Akiko
- The Nippon Dental University, School of Dentistry at Tokyo, Department of Periodontology
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- Sato Soh
- The Nippon Dental University, School of Dentistry at Tokyo, Department of Periodontology
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- Kamoi Hisahiro
- The Nippon Medical School Chiba Hokusoh Hospital Dental Clinic
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- Takayanagi Kazuaki
- The Nippon Dental University, School of Dentistry at Tokyo, Department of Periodontology
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- Ito Akiyo
- Tokyo Dental College, Department of Periodontics
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- Ito Taichi
- Tokyo Dental College, Department of Periodontics
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- Shibukawa Yoshihiro
- Tokyo Dental College, Department of Periodontics
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- Yamada Satoru
- Tokyo Dental College, Department of Periodontics
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- Kamoi Kyuichi
- The Nippon Dental University, School of Dentistry at Tokyo, Department of Periodontology
Bibliographic Information
- Other Title
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- アスコルビン酸ナトリウム配合歯磨剤の歯周炎に対する臨床効果
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Abstract
We evaluated the effect of dentifrice containing sodium ascorbate on periodontitis. Institutional ethics committee approval was obtained prior to the study. Subjects were 53 patients (15 men and 38 wemen, average age : 44.0 years) with periodontits enrolled in a double-blind clinical trial. We prepared 4 types of dentifrice, i.e., that containing zeolite and sodium monofluorophosphate (D-1), that adding 1.0% sodium ascorbate to D-1 (D-2), that adding 0.1% dl-α-tocopheryl acetate, 0.05% cetylpyridimium chloride, and 0.05% β-glycyrrhetinic acid to D-1 (D-3), and that adding 1.0% sodium ascorbate to D-3 (D-4). Dentifrice was randomly assigned to subjects, who were asked to brush twice daily for 4 weeks. Periodontal indices were measured at baseline, 2-, and 4-week evaluation. As a result for mean bleeding scores of D-2 and D-4, the dentifrices containing sodium ascorbate, a statistically significant difference was seen between baseline and 4-week evaluation (p<0.05, p<0.01). Of the 4 dentifrices, D-4 was the most effective. Statistically significant differences in mean gingival index (p<0.01), probing depth (p<0.01), and bleeding score (p<0.01) were seen between baseline and 4-week evaluation. These results suggest that a dentifrice containing sodium ascorbate is effective against periodontitis.
Journal
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- Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)
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Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) 46 (2), 137-142, 2004
JAPANESE SOCIETY OF PERIODONTOLOGY
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Details 詳細情報について
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- CRID
- 1390001204412718976
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- NII Article ID
- 10013297869
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- NII Book ID
- AN0019129X
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- ISSN
- 1880408X
- 03850110
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed