書誌事項
- タイトル別名
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- Pathological Evaluation of Small Breast Lesions with Abnormal Mammographic Microcalcification
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The incidence of small breast lesions with abnormal mammographic microcalcification (MC) is increasing, particularly as a result of the introduction of mammography (MMG) screening. MC is classified into five categories ; 90% of category 5 lesions are malignant and 90% of category 3 are benign. Microcalcified lesions are also divided into two types according to their constituent materials : type I (calcium oxalate) and type II (hydroxyapatite).The histopathological patterns of MC are usually subdivided into two types : necrotic (comedo carcinoma) and secretory (low-grade DCIS and benign lesions). However, few studies have made careful comparison between the findings of MMG and the histology of MC.<BR>In the present study, breast lumpectomy specimens of small lesions detected by the presence of MC were compared with their MMG findings using serial sections. Kossa staining was sometimes used to detect hydroxyapatite in the specimens more clearly.<BR>Reasons for discrepancy between MMG and histological finding were as follows : <BR>1) Abnormal quality and/or quantity of calcification in carcinoma, leading to classification as low malignancy on the basis of MMG.<BR>2) Grouped calcification with special histology, for example, sclerosing adenosis in fibroadenoma, leading to classification into a different category from that obtained by conventional MMG findings.<BR>3) Complex calcified lesions composed of benign and malignant small lesions.<BR>More careful histological examination of MC lesions using serial sections in relation to MMG findings is necessary.
収録刊行物
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- 日本乳癌検診学会誌
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日本乳癌検診学会誌 13 (2), 154-158, 2004
特定非営利活動法人 日本乳癌検診学会
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詳細情報 詳細情報について
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- CRID
- 1390001204461835136
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- NII論文ID
- 10013306395
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- NII書誌ID
- AN10398771
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- ISSN
- 18826873
- 09180729
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可