Noncovalent Combination of Oligoamine and Oligonucleotide as Totally Organic Site-selective RNA Cutter

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著者

    • SHI Yun
    • Research Center for Advanced Science and Technology, The University of Tokyo
    • NIIKURA Fumiya
    • Research Center for Advanced Science and Technology, The University of Tokyo
    • KUZUYA Akinori
    • Research Center for Advanced Science and Technology, The University of Tokyo
    • KOMIYAMA Makoto
    • Research Center for Advanced Science and Technology, The University of Tokyo

抄録

When a one-base gap was formed in substrate RNA by using two oligonucleotides, the phosphodiester linkage at the gap-site was activated and selectively hydrolyzed by ethylenediamine. This site-selective hydrolysis was further promoted by connecting two gap-forming oligonucleotides with 1,3-propanediol linker.

収録刊行物

  • Chemistry letters

    Chemistry letters 33(8), 1012-1013, 2004-08-05

    公益社団法人 日本化学会

参考文献:  21件中 1-21件 を表示

各種コード

  • NII論文ID(NAID)
    10013447776
  • NII書誌ID(NCID)
    AA00603318
  • 本文言語コード
    ENG
  • 資料種別
    SHO
  • ISSN
    03667022
  • データ提供元
    CJP書誌  J-STAGE 
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