Application of Ion-trap LC/MS/MS for Determination of Acrylamide in Processed Foods

• TSUTSUMIUCHI Kaname

  College of Bioscience & Biotechnology, Chubu University

• HIBINO Mariko

  College of Bioscience & Biotechnology, Chubu University

• KAMBE Mariko

  College of Bioscience & Biotechnology, Chubu University

• OISHI Kaori

  College of Bioscience & Biotechnology, Chubu University

• OKADA Masahiko

  College of Bioscience & Biotechnology, Chubu University

• MIWA Johji

  College of Bioscience & Biotechnology, Chubu University

• TANIGUCHI Hajime

  College of Bioscience & Biotechnology, Chubu University

Bibliographic Information

Other Title

• イオントラップ型LC/MS/MSによる加工食品中のアクリルアミドの定量

Abstract

Ion-trap LC/MS/MS was evaluated for use in the determination of acrylamide (AA) in processed foods. Multiple reaction monitoring (MRM) analysis of a series of AA standard solutions containing deuterium-labeled acrylamide (AA-d₃) as an internal standard was performed. A linear relationship between the concentration of AA and the ratio of peak area (AA/AA-d₃) in the extracted ion chromatogram (m/z 55, 58 derived from m/z 72, 75, respectively) was obtained over a wide range of 2-20,000 ng/mL. The quantification limit of AA was 2 ng/mL. In analyses of 37 commercial foods, AA was detected in a potato snack at the maximum value of 3,570 ng/g and found in 23 foods prepared or cooked at high temperature. The samples were analyzed in triplicate and the relative standard deviations (RSD) were less than 15% in many processed foods.

Journal

• Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)

  Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi) 45 (2), 95-99, 2004

  Japanese Society for Food Hygiene and Safety

Keywords

• acrylamide
• ion-trap MS
• LC/MS/MS
• processed food

Details

• CRID: 1390001204223777280
• NII Article ID: 10013518451
• NII Book ID: AN00117741
• DOI: 10.3358/shokueishi.45.95
• COI: 1:CAS:528:DC%2BD2cXkt1Gmtbg%3D
• ISSN: 18821006
• ISSN: 00156426
• NDL BIB ID: 6940925
• Web Site: https://agriknowledge.affrc.go.jp/RN/2030691573
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6940925
• Text Lang: en
• Data Source:
  • JaLC
  • IRDB
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed