Effects of Chard (<i>Beta vulgaris</i>L. var cicla) on the Liver of the Diabetic Rats: A Morphological and Biochemical Study
-
- OZSOY-SACAN Ozlem
- Department of Chemistry, Faculty of Engineering, Istanbul University
-
- KARABULUT-BULAN Omür
- Department of Biology, Faculty of Science, Istanbul University
-
- BOLKENT Sehnaz
- Department of Biology, Faculty of Science, Istanbul University
-
- YANARDAG Refiye
- Department of Chemistry, Faculty of Engineering, Istanbul University
-
- OZGEY Yasemin
- Department of Chemistry, Faculty of Engineering, Istanbul University
書誌事項
- タイトル別名
-
- Effects of Chard (Beta vulgaris L. var cicla) on the Liver of the Diabetic Rats: A Morphological and Biochemical Study
この論文をさがす
抄録
Chard (Beta vulgaris L. var cicla) is one of the medicinal herbs used by diabetics in Turkey. It has been reported to reduce blood glucose. We have investigated the effect of chard extracts on the liver by biochemical and morphological investigation. The plant extract was administered by the gavage technique to rats at a dose of 2 g/kg every d for 28 d, 14 d after experimental animals were made diabetic. In the diabetic group, some degenerative changes were observed by light and electron microscope examination, but degenerative changes decreased or were not observed in the diabetic group given chard. In the diabetic group, blood glucose levels, serum alanine, aspartate transaminase, alkaline phosphatase activities, total lipids, sialic and uric acid levels, liver lipid peroxidation (LPO), and nonenzymatic glycosylation (NEG) levels increased, while blood glutathione, body weight, and liver glutathione (GSH) levels decreased. The diabetic group given chard, serum alanine, aspartate transaminase, alkaline phosphatase activities, total lipid level, sialic and uric acid levels, blood glucose levels, and liver LPO and NEG levels decreased, but the other values increased. As a result of all the morphological and biochemical findings obtained, it was concluded that the extract of this plant has a protective effect on the liver in diabetes mellitus.
収録刊行物
-
- Bioscience, Biotechnology, and Biochemistry
-
Bioscience, Biotechnology, and Biochemistry 68 (8), 1640-1648, 2004
公益社団法人 日本農芸化学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282681452973312
-
- NII論文ID
- 10013520508
-
- NII書誌ID
- AA10824164
-
- ISSN
- 13476947
- 09168451
-
- NDL書誌ID
- 7066814
-
- PubMed
- 15322346
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可