Tracheo-bronchitis Associated with Crohn's Disease Improved on Inhaled Corticotherapy

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  • KINEBUCHI Shin-ichi
    Division of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Niigata University
  • OOHASHI Kazumasa
    Division of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Niigata University
  • TAKADA Toshinori
    Division of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Niigata University
  • MORIYAMA Hiroshi
    Division of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Niigata University
  • YOSHIZAWA Hirohisa
    Division of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Niigata University
  • KOBAYASHI Osamu
    Department of Respiratory Medicine, Niigata Prefectural Central Hospital
  • SUZUKI Eiichi
    Department of General Medicine, Niigata University Medical and Dental Hospital
  • GEJYO Fumitake
    Division of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Niigata University

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Abstract

We report a case of tracheo-bronchitis in Crohn's disease. A 23-year-old Japanese woman who had been diagnosed with Crohn's disease three years previously was hospitalized. She had been suffering from dry cough for one month. Computed tomography of the chest revealed marked thickening of the tracheal wall. Bronchoscopy showed erythematous and edematous mucosa with diffuse whitish granular lesions in the trachea and bronchi. The bronchial biopsy specimens showed non-specific inflammatory infiltrates consisting of lymphocytes and plasma cells, and hyperplasia of bronchial glands. Inhaled corticotherapy, fluticasone propionate 800 μg/day, was effective for both the inflammatory mucosa and thickened tracheal wall.

Journal

  • Internal Medicine

    Internal Medicine 43 (9), 829-834, 2004

    The Japanese Society of Internal Medicine

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