On-line capillary electropho resis-Mass spectrometry

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  • オンラインキャピラリー電気泳動-質量分析法
  • オンライン キャピラリー デンキ エイドウ シツリョウ ブンセキホウ

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Abstract

A brief review of interfaces for on-line coupling of capillary electrophoresis (CE) and mass spectrometry (MS) is presented. To enable the CE-MS system, electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) were introduced as MS interfaces for connecting with CE instruments, while the partial-filling method was developed to suppress the introduction of non-volatile components or additives in CE buffers as well as ionic species such as ionic micelles into the MS interface. Strategy for the coupling of micellar electrokinetic chromatography (MEKC) and MS is also discussed. Examples of CE-MS are briefly shown.

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