80年代と90年代に初診した15歳未満発見糖尿病患者の合併症頻度の比較

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タイトル別名
  • Effect of Diabetes Type and First Calendar Year Visit to Diabetes Center on Prevalence of Microvascular Complications in Diabetic Patients Diagnosed before the Age of 15
  • 80ネンダイ ト 90ネンダイ ニ ショシン シタ 15サイ ミマン ハッケン トウニョウビョウ カンジャ ノ ガッペイショウ ヒンド ノ ヒカク

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We studied the case-controlled effect of diabetes type and the first calendar year visit to the Diabetes Center on the prevalence of microvascular complications in early-onset diabetic patients.Subjects had type 2 diabetes diagnosed before the age of 15 and visited the Center inthe 1980s (1980-1988, n=42) and 1990s (1989-1998, n=42). Age-and duration-matched type 1 diabetic patients visited in the 1980s (n=104) and 1990s (n=91). The prevalence of diabetic complications in the80s group was obtained in 1988 and that of the 90s group in 1998. The prevalence of proliferative retinopathy was higher and of simple retinopathy lower in type 2 than in type 1 in both groups.The prevalence of proliferative retinopathy and clinical nephropathy tended to be higher with increasing calender year in both types, although simple retinopathy was significantly lower in type 1 diabetics in the 90s than in the 80s (p<0.005). About half of 90s type 2 diabetics had undergone intermittent treatment in the past, and theyexperienced a significant deterioration in complications.

収録刊行物

  • 糖尿病

    糖尿病 47 (7), 521-526, 2004

    一般社団法人 日本糖尿病学会

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