A False Positive Serum Digoxin Level in Elderly Patients

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著者

    • YAMAMOTO Takatsugu
    • 東京医科歯科大学難治疾患研究所社会医学研究部門予防医学教室 Department of Preventive Medicine, Division of Social Medicine, Medical Research Institute, Tokyo Medical and Dental University
    • SANAKA Masaki
    • 東京医科歯科大学難治疾患研究所社会医学研究部門予防医学教室 Department of Preventive Medicine, Division of Social Medicine, Medical Research Institute, Tokyo Medical and Dental University
    • KOIKE Yuichi
    • 東京医科歯科大学難治疾患研究所社会医学研究部門予防医学教室 Department of Preventive Medicine, Division of Social Medicine, Medical Research Institute, Tokyo Medical and Dental University
    • MINESHITA Satoru
    • 東京医科歯科大学難治疾患研究所社会医学研究部門予防医学教室 Department of Preventive Medicine, Division of Social Medicine, Medical Research Institute, Tokyo Medical and Dental University

抄録

We investigated the serum digoxin concentration (SDC) by TDx Digoxin II assay in 113 elderly patients who were not receiving any cardiac glycosides. Most of the falsely elevated SDCs were regarded as negligible clinically, whereas some of the values were markedly high. It was of interest that all of four false positive SDCs exceeding 0.3 ng/ml were derived from patients undergoing continuous intravenous drip infusion with sodium containing solution at the time of sampling.<BR>In conclusion, TDx Digoxin II may be applicable to the elderly who are not receiv ing intravenous sodium infusion treatment. However, since false positive SDC can become elevated in aged patients undergoing this therapy, careful attention must be paid to such patients.

収録刊行物

  • 臨床薬理 = JAPANESE JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

    臨床薬理 = JAPANESE JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS 27(2), 481-488, 1996-06-30

    一般社団法人 日本臨床薬理学会

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各種コード

  • NII論文ID(NAID)
    10013850094
  • NII書誌ID(NCID)
    AN0025404X
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    03881601
  • データ提供元
    CJP書誌  J-STAGE 
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